Adjunctive tests cannot replace scalpel biopsy for oral cancer diagnosis

Hemoglobin A1c for the diagnosis of diabetes: To replace or to guide oral glucose tolerance tests?

UNLABELLED Aims/Introduction:  To evaluate if hemoglobin A1c (A1C) can replace the use of the oral glucose tolerance test (OGTT) to diagnose diabetes in Chinese patients. MATERIALS AND METHODS   Subjects without pre-existing diabetes were included in this community-based study. Each participant received a 75-g OGTT and A1C tests. RESULTS   A total of 1362 subjects, 512 men and 850 women, ag...

Novel non-invasive adjunctive techniques for early oral cancer diagnosis and oral lesions examination.

Oral cancer is a potentially fatal disease with an increasing incidence and an unchanged 5-year mortality rate. Unfortunately, oral cancer is often still late diagnosed, which leads to an increase in the likelihood of functional impairment due to treatment and mortality rate. Definitive diagnosis of oral cancer must be confirmed by scalpel biopsy and histological assessment. However despite its...

Needle Core Biopsy Should Replace Fine Needle Aspiration Cytology in Breast Lesions Diagnosis

Biochemical non-invasive assessment of liver fibrosis cannot replace biopsy in HIV-HCV coinfected patients.

BACKGROUND AND RATIONALE The liver biopsy has been considered the gold standard for the diagnosis and quantification of fibrosis. However, this method presents limitations. In addition, the non-invasive evaluation of liver fibrosis is a challenge. The aim of this study was to validate the fibrosis cirrhosis index (FCI) index in a cohort of human immunodeficiency virus (HIV)/hepatitis C virus (H...

Adjunctive techniques for oral cancer examination and lesion diagnosis: a systematic review of the literature.

BACKGROUND Adjunctive techniques that may facilitate the early detection of oral premalignant and malignant lesions (OPML) have emerged in the past decades. METHODS The authors undertook a systematic review of the English-language literature to evaluate the effectiveness of toluidine blue (TB), ViziLite Plus with TBlue (Zila Pharmaceuticals, Phoenix), ViziLite (Zila Pharmaceuticals), Microlux...